Keep Current with the Latest in Cell Biology Research
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NIH awards $16.4 million to establish multi-institution hepatitis C vaccine development center
[Scripps Research] The National Institutes of Health (NIH) has awarded $16.4 million over five years to establish a new U19 “Cooperative Center for Rational hepatitis C virus Vaccine Design & Evaluation,” which will bring together scientists to uncover how the virus escapes immune responses and create vaccine candidates.
First Person Infected with Rare Shamonda Virus: What We Know
[Nature] An individual with cancer in France has become the first person known to contract the Shamonda virus, after an outbreak in livestock in Europe that was first identified in July 2026.
TXST Biologist Receives NIH Grant to Uncover How Malaria Parasites Invade Blood Cells
[Texas State University] Texas State University biologist Sumit Mukherjee, Ph.D., has secured a four-year, $752,000 grant, from the National Institute of Allergy and Infectious Diseases to uncover how malaria parasites build the structures that allow them to invade human red blood cells.
Early Risk Stratification of COVID-19 Associated Cytokine Storm Using a Four-Cytokine Cumulative Score: A Retrospective Cohort Study
[Journal of Medical Virology] Scientists aimed to identify early predictive biomarkers, characterize their lead times, and develop a cumulative cytokine score for early risk stratification of COVID-19-associated cytokine storm.
Sex Differences in Inflammation, Mitochondrial Function, and Energy Sensing during Early Recovery from COVID 19 in Older Adults
[Scientific Reports] Researchers investigated sex differences among post-COVID-19 patients during the early recovery phase, as emerging evidence indicates that sex critically influences post-COVID-19 outcomes, particularly in older adults.
Nectin-4 mediates rubella virus entry in airway and placental cells
[Nature] Using proximity biotin labelling-based proteomics coupled with CRISPR–Cas9 validation, the authors identify nectin-4 as a functional rubella virus entry receptor.
Innate Sensor Responses Set a Supra-Unitary Threshold for Viral Replication
[Cell] Investigators single-cell analysis revealed that viral replication requires a supra-unitary viral genome input, significantly more than one, which they defined as the virion input threshold for replication.
Systemic Exposure to Typhoid Toxin Primes the Murine Vascular Endothelium for Intestinal Perforation during Salmonella Typhi Infection
[Nature Microbiology] Using sequential exposure to the PltC form of typhoid toxin followed by oral Salmonella Typhi infection, scientists developed a mouse model of late-stage human typhoid, when circulating toxin precedes the onset of intestinal pathology.
B Cell Follicles in the Secondary Lymphatic Tissues Act As a Critical Microanatomical Niche for Sustained Viral Replication, Virus-Host Interaction, and Damage during Chronic...
[Journal of Medical Virology] Researchers investigated viral spatial distribution patterns and the corresponding lymphatic tissue structural alterations in simian immunodeficiency virus chronically infected rhesus macaques.
Dapagliflozin Inhibits BK Polyomavirus Replication via AMPK Signaling
[Journal of Medical Virology] The authors investigated whether the SGLT2 inhibitor dapagliflozin could suppress BK polyomavirus replication, providing a strong rationale for evaluating SGLT2 inhibitors as a novel strategy to reduce the severity of infection in transplant recipients.
Dengue Virus Controlled Human Challenge Reveals That Preexisting Immunity Shapes Viral Replication and Broadly Protective Responses
[Science Translational Medicine] Scientists conducted a phase I clinical trial with 45 healthy adults to test whether secondary infection challenge with a heterotypic, full-length, attenuated dengue virus increases viremia and immunogenicity compared with primary and tertiary infection.
Human Hair-Bearing Skin Organoids Reveal Cell Type-Specific Susceptibility and Innate Immune Responses to Herpes Simplex Virus 1
[Science Advances] Researchers used human hair–bearing skin organoids and combined single-cell spatial transcriptomics with imaging to map herpes simplex virus 1 viral spread and host responses across skin architecture.