The emerging role of BMP signaling in lymphatic vessel biology will be highlighted within the framework of BMP signaling in the circulatory vasculature.
[International Journal of Molecular Sciences]
Hydrogel wound dressings carrying antibacterial silver nanoparticles and vascular endothelial growth factor with predetermined release profiles were utilized to study the physiological response of the wound in a mouse model.
Single-cell RNA sequencing across ezh1 genotypes revealed a dropout of ezh1+/− cells among arterial endothelium associated with positive regulation of gene transcription.
[Stem Cell Reports]
6445218 XHEAA4ME items 1 apa default asc 1
Soto, R. A., Najia, M. A. T., Hachimi, M., Frame, J. M., Yette, G. A., Rocha, E. L. da, Stankunas, K., Daley, G. Q., & North, T. E. (2021). Sequential regulation of hemogenic fate and hematopoietic stem and progenitor cell formation from arterial endothelium by Ezh1/2. Stem Cell Reports, 0(0). https://doi.org/10.1016/j.stemcr.2021.05.014 Cite
Scientists used a modular tissue-engineering approach, embedding SUP microgels loaded with human umbilical vein endothelial cells into a 3D SUP hydrogel containing human dermal fibroblast neonatal cells to trigger angiogenesis.
[ACS Applied Materials & Interfaces]
6445218 SYMS9XTH items 1 apa default asc 1
Scientists examined the changes in mechanical tension of syndecan-1, a cell surface proteoglycan that is an integral part of the glycocalyx, in response to substrate stiffness and fluidic shear stress.
6445218 959G99EX items 1 apa default asc 1
Le, V., Mei, L., Voyvodic, P. L., Zhao, C., Busch, D. J., Stachowiak, J. C., & Baker, A. B. (2021). Molecular tension in syndecan-1 is regulated by extracellular mechanical cues and fluidic shear stress. Biomaterials, 275, 120947. https://doi.org/10.1016/j.biomaterials.2021.120947 Cite
Inspired by the specific neutrophil–endothelium interaction, investigators designed neutrophil-camouflaged magnetic nanoprobes that can be used to target activated endothelial cells for improved neuroinflammation imaging.
6445218 EFLFG2RJ items 1 apa default asc 1
MiR-126 expression, as well as EGFL7, in SSc-MVECs and skin, was significantly down-regulated in association with increased expression of SPRED1 and PIK3R2 and diminished response to VEGF.
[Journal of Cellular and Molecular Medicine]
6445218 RVKZWTIL items 1 apa default asc 1
Sr–CPHC facilitated the migration and tube formation of human umbilical vein endothelial cells in vitro and up-regulated the expression of the vascular endothelial growth factor and Angiopoietin-1.
[Journal of Materials Chemistry B]
6445218 LNXFA7CE items 1 apa default asc 1
Wu, X., Tang, Z., Wu, K., Bai, Y., Lin, X., Yang, H., Yang, Q., Wang, Z., Ni, X., Liu, H., & Yang, L. (2021). Strontium–calcium phosphate hybrid cement with enhanced osteogenic and angiogenic properties for vascularised bone regeneration. Journal of Materials Chemistry B. https://doi.org/10.1039/D1TB00439E Cite
Buried in a bill approved by the US Senate to help the United States compete with China is language that is drawing fire from human genome researchers. It would require the NIH to develop new security protocols aimed at preventing the misuse of US-funded genomic data by China and other nations.
6445212 nan items 1 apa default asc 1
Researchers used a modified approach to differentiate induced pluripotent stem cells into corneal endothelial-like cells (CECs). After the identification of differentiated CECs, the CECs were injected into the anterior chambers of the eyes of a rabbit model of bullous keratopathy.
[Stem Cells and Development]
6445218 RBVCBM2F items 1 apa default asc 1
Sun, B., Bikkuzin, T., Li, X., Shi, Y., & Zhang, D. H. (2021, June 15). Human Induced pluripotent stem cells-derived corneal endothelial-like cells promote corneal transparency in a rabbit model of bullous keratopathy [Research-article]. Https://Home.Liebertpub.Com/Scd. https://doi.org/10.1089/scd.2020.0205 Cite
Scientists discuss the evidence for nitric oxide as a critical player of placental development and function, with a special focus on endothelial nitric oxide synthase vascular effects.
[Journal of Cellular Physiology]