Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

A Novel Multifunctional Chitosan-Gelatin/Carboxymethyl Cellulose-Alginate Bilayer Hydrogel Containing Human Placenta Extract for Accelerating Full-Thickness Wound Healing

[International Journal Of Biological Macromolecules] Researchers present a multifunctional bi-layer hydrogel incorporating human placenta extract (HPE) for accelerating full-thickness wound healing through sustained HPE release, inhibition of bacteria invasion, and promotion of cell proliferation.

Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Kidney Disease by Modulating the T Helper 17 Cell/ Regulatory T-Cell Balance through the Programmed Death 1...

[Diabetes Obesity & Metabolism] The authors investigated the therapeutic effects and immunomodulatory mechanisms of human placenta-derived mesenchymal stem cells in diabetic kidney disease.

Management of Retinitis Pigmentosa Via Wharton’s Jelly-Derived Mesenchymal Stem Cells or Combination with Magnovision: Three-Year Prospective Results

[Stem Cells Translational Medicine] Researchers investigated whether the natural progression rate of retinitis pigmentosa could be decreased with subtenon Wharton’s jelly-derived MSC application alone, or combination with Magnovision.

Successful Cord Blood Transplantation for del7q Myelodysplastic Syndrome in Pearson Marrow Pancreas Syndrome

[American Journal Of Hematology] Scientists reported successful cord blood transplantation with four years of follow-up for a child with Pearson marrow pancreas syndrome who developed myelodysplastic syndrome with deletion of chromosome 7q.

Umbilical Cord Mesenchymal Stem Cell-Derived Apoptotic Extracellular Vesicles Ameliorate Cutaneous Wound Healing in Type 2 Diabetic Mice via Macrophage Pyroptosis Inhibition

[Stem Cell Research & Therapy] Umbilical cord MSCs were cultured in vitro and apoptosis was induced. ApoEVs were extracted and identified and used in a type 2 diabetes mellitus mouse cutaneous wound model to evaluate their efficacy.

Impact of Ferroptosis on Preeclampsia: A Review

[Biomedicine & Pharmacotherapy] The authors explore the new therapeutic target of preeclampsia through oxidative stress in ferroptosis.

NIH Upholds Controversial Plan to Step Up Oversight of Foreign Collaborators

[Nature News] The US biomedical agency tweaked its new policy after an outcry from researchers, but will forge ahead.

Targeted Delivery of RGD-CD146+CD271+ Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Promotes Blood–Spinal Cord Barrier Repair after Spinal Cord Injury

[ACS Nano] Specific subpopulations of CD146+CD271+ umbilical cord MSCs were isolated, from which engineered exosomes with targeted neovascularization function were obtained through gene transfection.

Fluid Shear Stress Induces a Shift from Glycolytic to Amino Acid Pathway in Human Trophoblasts

[Cell & Bioscience] Placental tissue from pregnancies with intrauterine growth restriction were exposed to high shear rates and showed also decreased glutamic-oxaloacetic transaminase 2, while GLUT1 was unchanged and glycolytic rate-limiting enzymes showed a trend to be upregulated.

Zika Virus Targets Human Trophoblast Stem Cells and Prevents Syncytialization in Placental Trophoblast Organoids

[Nature Communications] Newly developed human trophoblast stem cells (hTSC)-derived trophoblast organoid, researchers demonstrated that Zika virus infection disrupted the structure of mature hTSC-organoids and inhibited syncytialization.

Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Neuroinflammation and Oxidative Stress through the NRF2/NF-κB/NLRP3 Pathway

[CNS Neuroscience & Therapeutics] The effects of human umbilical cord-MSC-derived exosomes on inflammatory cytokine expression, oxidative stress, and microglia polarization were studied by immunofluorescence and western blotting.

Impact of Administering Umbilical Cord-Derived Mesenchymal Stem Cells to Cynomolgus Monkeys with Endometriosis

[Reproductive Medicine And Biology] Laparoscopic findings showed exacerbation of endometriosis after intraperitoneal umbilical cord-MSC administration, although no changes were observed in the control group.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.