Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

Human Fetal Membrane-Mesenchymal Stromal Cells Generate Functional Spinal Motor Neurons In Vitro

[iScience] Scientists demonstrated that human fetal membrane-MSCs could give rise to spinal motor neurons, by the sequential exposure to specific factors that induced a neuralization, caudalization and ventralization of undifferentiated cells

Engineering Placenta-Like Organoids Containing Endogenous Vascular Cells from Human-Induced Pluripotent Stem Cells

[Bioengineering & Translational Medicine] Researchers presented a new strategy to establish placenta-like organoids with vascular-like structures from human-induced pluripotent stem cells in a defined three-dimensional culture system.

Regenerative Effect of Umbilical Cord-Derived Mesenchymal Stromal Cells in a Rat Model of Established Limb Ischemia

[Circulation Journal] Investigators assessed the tissue regenerative potential of umbilical cord-derived MSCs, which could potentially be an ideal cell source, in a rat model of established ischemia.

Umbilical Cord Maternal Microchimerism in Normal and Preeclampsia Pregnancies

[Reproductive Sciences] Scientists evaluated maternal microchimerism in umbilical cord blood (CB) from normal and preeclampsia pregnancies. DNA from CB mononuclear cells following placental deliveryand maternal blood was extracted and genotyped.

Unrelated Umbilical Cord Blood Can Improve the Prognosis of Haploidentical Hematopoietic Stem Cell Transplantation

[Stem Cell Research & Therapy] Researchers showed that neither acute graft versus host disease (aGVHD) nor chronic GVHD was increased in the umbilical cord blood-haplo hematopoietic stem cell transplantation group, and the engraftment and infection rates were similar between the two groups.

Multifaceted Characterization of the Biological and Transcriptomic Signatures of Natural Killer Cells Derived from Cord Blood and Placental Blood

[Cancer Cell International] The authors took advantage of the “3IL”-based strategy for high-efficient generation of natural killer (NK) cells from umbilical cord blood and placental blood, respectively.

NINJ1 Triggers Extravillous Trophoblast Cell Dysfunction through Blocking the STAT3 Signaling Pathway

[Genes & Genomics] Researchers investigated the effect of nerve injury-induced protein 1 (NINJ1) on trophoblast behaviors and pregnancy loss.

Effects of Polycyclic Aromatic Hydrocarbons on Gestational Hormone Production in a Placental Cell Line: Application of Passive Dosing to In Vitro Tests

[Ecotoxicology and Environmental Safety] Investigators studied the effects of some airborne polycyclic aromatic hydrocarbons on beta human chorionic gonadotropin and progesterone production by using a syncytial BeWo cell line as a placental model.

Oxidative Stress, Lipid Peroxidation and Premature Placental Senescence in Preeclampsia

[Archives of Biochemistry and Biophysics] The authors summarize the current knowledge on premature placental senescence and the role of oxidative stress and lipid oxidation-derived aldehydes in this process, as well as their links with preeclampsia pathogenesis.

Oyen and Team Receive Funding to Study Placental Function

[Washington University in St. Louis] Wellcome Leap has awarded Michelle Oyen, an associate professor of biomedical engineering at Washington University in St. Louis’ McKelvey School of Engineering, a multiyear contract to advance methods to assess placental function.

Human Fetal Membrane-Mesenchymal Stromal Cells Generate Functional Spinal Motor Neurons In Vitro

[iScience] Scientists demonstrated that human fetal membrane-MSCs could give rise to spinal motor neurons, by the sequential exposure to specific factors that induced a neuralization, caudalization, and ventralization of undifferentiated cells.

3D In Vitro Cultures of Human Bone Marrow and Wharton’s Jelly Derived Mesenchymal Stromal Cells Show High Chondrogenic Potential

[Frontiers in Bioengineering and Biotechnology] Chondrogenic potentials of 3D high-density cultures of Bone Marrow and Wharton’s Jelly-derived MSCs was investigated by chondrogenesis- and cytokine-related gene expression over a 16-day culture period supplemented with human transforming growth factor.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.

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