Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

Spatial Multiomics Map of Trophoblast Development in Early Pregnancy

[Nature] Scientists used a cellular map to infer the possible transcription factors mediating extravillous trophoblast cells (EVT) invasion, and showed that they are preserved in in vitro models of EVT differentiation from primary trophoblast organoids, and trophoblast stem cells.

Protective Effects of Human Amniotic Membrane Derived Mesenchymal Stem Cells (hAMSCs) Secreted Factors on Mouse Spermatogenesis and Sperm Chromatin Condensation Following Unilateral Testicular Torsion

[Annals Of Anatomy-Anatomischer Anzeiger] Investigators evaluated the protective effects of hAMSCs secreted factors on mouse sperm chromatin condensation and spermatogenesis improvement after ischemia/reperfusion injury.

MicroRNAs of Extracellular Vesicles Derived from Mesenchymal Stromal Cells Alleviate Inflammation in Dry Eye Disease by Targeting the IRAK1/TAB2/NF-κB Pathway

[Ocular Surface] Scientists investigated the efficacy and mechanisms of human umbilical cord-derived MSC-derived extracellular vesicles in a mouse model of desiccation-induced dry eye disease.

Schisandrin B Improves the Hypothermic Preservation of Celsior Solution in Human Umbilical Cord Mesenchymal Stem Cells

[Tissue Engineering and Regenerative Medicine] The authors investigated the protective effects of Schisandrin B on the hypothermic preservation of human umbilical cord MSCs isolated from Wharton’s jelly.

Impact of the Source of Hematopoietic Stem Cells on Immune Reconstitution after Transplantation: A Systematic Review

[European Journal Of Haematology] Scientists analyze the kinetic of immune reconstitution among umbilical cord blood, peripheral blood, and bone marrow in hematopoietic stem cell transplant patients by focusing on natural killer cells, B and T lymphocytes, and neutrophils.

In Vitro Evaluation of Genipin-Crosslinked Gelatin Hydrogels for Vocal Fold Injection

[Scientific Reports] Some selected formulations were proceeded with rheology, pore size, chemical analysis and in vitro cellular activity of Wharton's Jelly Mesenchymal Stem Cells, to determine the safety application of the selected hydrogels, for future cell delivery prospect.

Hypoxia-Treated Umbilical Mesenchymal Stem Cell Alleviates Spinal Cord Ischemia-Reperfusion Injury in SCI by Circular RNA circOXNAD1/ miR-29a-3p/ FOXO3a Axis

[Biochemistry And Biophysics Reports] Researchers studied the therapeutic potential of hypoxia-induced exosomal circular RNA OXNAD1 from human umbilical cord MSCs against spinal cord ischemia reperfusion.

Human Umbilical Cord Mesenchymal Stem Cells Ameliorate Acute Graft versus Host Disease by Elevating Phytosphingosine

[Experimental Hematology] Investigators revealed the efficacy of human umbilical cord MSCs in alleviating acute graft-versus-host disease in a murine model, with striking changes in metabolism and significantly elevated phytosphingosine levels due to sphingolipid metabolism.

Placenta Powder-Infused Thiol-Ene PEG Hydrogels as Potential Tissue Engineering Scaffolds

[Biomacromolecules] Placenta powder, made from decellularized human placenta, was physically incorporated into synthetic poly(ethylene glycol)-based hydrogels via ultraviolet-initiated thiol-ene coupling.

Placental Mesenchymal Stem Cells Ameliorate NLRP3 Inflammasome-Induced Ovarian Insufficiency by Modulating Macrophage M2 Polarization

[Journal of Ovarian Research] Injection of human placental MSCs improved ovarian function and reproductive ability of premature ovarian insufficiency rats compared to the sham and hormone groups.

A Differentiation Roadmap of Murine Placentation at Single-Cell Resolution

[Cell Discovery] To decipher cell compositions and developmental processes, the authors systematically profiled the single-cell transcriptomes of trophoblast cells from extraembryonic tissues and placentae at one-day intervals.

Human Umbilical Cord Mesenchymal Stem Cells Conditioned Medium Exerts Anti-Tumor Effects on KGN Cells in a Cell Density-Dependent Manner through Activation of the Hippo...

[Stem Cell Research & Therapy] Researchers explored the effect of human umbilical cord MSCs-conditioned medium on granulosa tumor cell line cells at low or high density.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.