Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

Endogenous Follistatin-Like 1 Guarantees the Immunomodulatory Properties of Mesenchymal Stem Cells during Liver Fibrotic Therapy

[Stem Cell Research & Therapy] Investigators characterized the potential role of follistatin-like 1 in MSC-based anti-fibrotic therapy and further elucidated the mechanisms underlying its action.

Umbilical Cord Mesenchymal Stem Cells and Breast Cancer: A Good Therapeutic Candidate or Not? A Minireview

[Molecular Biology Reports] The authors review the influences of umbilical cord-derived MSCs on breast cancer and summarize this with a focus on the molecular mechanisms involved in its pathogenesis and treatment.

Orca Bio Announces the Precision-T Phase III Study Is Open and Enrolling Patients at Transplant Centers across the US

[Orca Bio] Orca Bio announced Precision-T, its pivotal Phase III study, is open, enrolling and treating patients at clinical trial sites including Stanford Health Care, City of Hope, Winship Cancer Institute of Emory University, Sarah Cannon Research Institute, Ronald Reagan UCLA Medical Center and Oregon Health & Science University.

Human Umbilical Cord Mesenchymal Stem Cells Derived Extracellular Vesicles Regulate Acquired Immune Response of Lupus Mouse In Vitro

[Scientific Reports] Scientists investigated whether human umbilical cord MSCs derived extracellular vesicles could regulate abnormal immune responses of T cells or B cells in systemic lupus erythematosus.

Co-culture Pellet of Human Wharton’s Jelly Mesenchymal Stem Cells and Rat Costal Chondrocytes as a Candidate for Articular Cartilage Regeneration: In Vitro and In...

[Stem Cell Research & Therapy] Researchers directly co-cultured rat costal chondrocytes and human Wharton’s jelly MSCs cells were evaluated as a candidate to regenerate articular cartilage.

Effect of Cell Derived Matrices on Growth and Differentiation of Human Wharton’s Jelly Derived Mesenchymal Stem Cells

[Cell Tissues Organs] Investigators tested if the growth of human Wharton’s jelly derived MSCs could be enhanced when cultured on their own cell derived matrices.

Decreased Expression of Hypoxia-Inducible Factor 1α (HIF-1α) in Cord Blood Monocytes under Anoxia

[Pediatric Research] The effect of low oxygen partial pressure on HIF-1α expression and its targets phagocytosis, reactive oxygen species production and vascular endothelial growth factor secretion was compared in vitro between immune cells from adult peripheral blood and cord blood using anoxia.

SOX9 Reprograms Endothelial Cells by Altering the Chromatin Landscape

[Nucleic Acids Research] Using human umbilical vein endothelial cells (HUVECs), researchers showed that SOX9 expression alone was sufficient to activate mesenchymal genes and steer endothelial cells towards a mesenchymal fate.

UF Center for Regenerative Medicine Recruiting for Trial on Potential Therapy for Autoimmune Disorders

[University of Florida Health] The University of Florida Center for Regenerative Medicine announced the launch of a clinical trial to test safe dosages of umbilical cord-derived stem cells in the treatment of two debilitating autoimmune disorders.

Human Umbilical Cord-Derived Mesenchymal Stem Cells Ameliorate Skin Aging of Nude Mice Through Autophagy-Mediated Anti-Senescent Mechanism

[Stem Cell Reviews and Reports] To clarify how human umbilical cord-derived MSCs (hucMSCs) work on skin aging, scientists employed skin-aging model of human dermal fibroblasts to conduct in vitro assays by applying conditional medium of hucMSCs.

miR-126-3p Containing Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Angiogenesis and Attenuate Ovarian Granulosa Cell Apoptosis in a Preclinical Rat Model...

[Stem Cell Research & Therapy] Researchers investigated the role of miR-126-3p-modified human umbilical cord MSCs derived exosomes on the treatment of premature ovarian failure.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.