Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

Translating MSC Therapy in the Age of Obesity

[Frontiers in Immunology] Investigators look to cancer immunotherapy as a model for the challenges MSCs may face in obese environments.

MicroRNA-206 Down-Regulated Human Umbilical Cord Mesenchymal Stem Cells Alleviate Cognitive Decline in D-Galactose-Induced Aging Mice

[Cell Death Discovery] After daily subcutaneous injection of D-gal (500 mg/kg/d) for 8 weeks, 17-week-old male C57BL/6 J mice were stem cells transplanted by lateral ventricular localization injection.

Engineering Bioactive Nanoparticles to Rejuvenate Vascular Progenitor Cells

[Communications Biology] Scientists reported a strategy to rejuvenate circulating vascular progenitor cells by conjugation of drug-loaded liposomal nanoparticles directly to the surface of gestational diabetes mellitus-exposed endothelial colony-forming cells.

An Optimized Method for Obtaining Clinical-Grade Specific Cell Subpopulations from Human Umbilical Cord-Derived Mesenchymal Stem Cells

[Cell Proliferation] Scientists established a general operation process for obtaining high-quality clinical-grade cell subpopulations from human umbilical cord MSCs based on particular markers.

Modelling Human Placental Villous Development: Designing Cultures That Reflect Anatomy

[Cellular and Molecular Life Sciences] The authors outline the current understanding of placental development, and critically considers the range of established and emerging culture models used to study this, with a focus on those derived from primary tissue.

Wharton’s Jelly Mesenchymal Stem Cell-Derived Small Extracellular Vesicles as Natural Nanoparticles to Attenuate Cartilage Injury via microRNA Regulation

[International Journal of Pharmaceutics] Investigators identified natural small extracellular vesicles harvested from Wharton’s jelly mesenchymal stem cells.

Long Noncoding RNA PVT1 Accelerates the Growth of Placental Trophoblasts in Preeclampsia through the microRNA-24-3p/HSD11B2 Axis

[Molecular Reproduction and Development] Plasmacytoma variant translocation 1(PVT1), miR-24-3p, and HSD11B2 expression levels in normal placental tissues and preeclampsia placental tissues were defined

Outcome of Human Umbilical Cord Blood Stem Cell Transplantation (CBT) for Acute Myeloid Leukemia in Patients Achieving First Complete Remission after One versus Two...

[Bone Marrow Transplantation] Researchers compared transplantation outcomes of adult patients with acute myeloid leukemia that underwent CBT in CR1 following 1 versus 2 induction courses.

Comparison of Biological Characteristics of Human Adipose- and Umbilical Cord- Derived Mesenchymal Stem Cells and Their Effects on Delaying the Progression of Osteoarthritis in...

[Acta Histochemica] Umbilical cord-derived-MSCs and adipose-derived-MSC were isolated from the umbilical cord and subcutaneous fatty tissue of humans respectively and identified by flow cytometry.

Controllable Manipulation of Alginate-Gelatin Core-Shell Microcarriers for HUMSCs Expansion

[International Journal of Biological Macromolecules] Researchers studied the attachment and proliferation of human umbilical cord-MSCs (HUMSCs) on alginate-gelatin core-shell microcarriers with different mechanical strengths modulated by gelatin coating, and the harvested cells were characterized to verity their differentiation potential.

Generation of Universal Natural Killer Cells from a Cryopreserved Cord Blood Mononuclear Cell-Derived Induced Pluripotent Stem Cell Library

[Febs Open Bio] The authors prepared human leukocyte antigen (HLA)-matched iPSCs using HLA common haplotype homozygous donors from cryopreserved human cord blood sourced from the Tianjin Cord Blood Public Bank.

Intravenously Transplanted Mesenchymal Stromal Cells: A New Endocrine Reservoir for Cardioprotection

[Stem Cell Research & Therapy] MSCs were isolated from human placenta tissue, and DF-MSCs or Gluc-MSCs were generated by transduced with firefly luciferase/enhanced green fluorescence protein or Gaussia luciferase lactadherin fusion protein.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.