Umbilical & Placental Cell News

Umbilical & Placental Cell News is an online resource dedicated to sharing the newest publications, reviews, and news updates in the field of umbilical and placental cell research.

Mechanisms of Wharton’s Jelly-Derived MSCs in Enhancing Peripheral Nerve Regeneration

[Scientific Reports] Wharton's jelly-MSCs were isolated from umbilical cords, and acellular nerve grafts (ANGs) or WJ-MSCs-loaded ANGs were transplanted in injury animal model.

Mesenchymal Stem Cells Prevent H7N9 Virus Infection via Rejuvenating Immune Environment to Inhibit Immune-Overactivity

[Biochimica Et Biophysica Acta-Molecular Basis Of Disease] ICR mice were pretreated with human umbilical cord (hUC) MSCs and then infected with the influenza H7N9 virus. Weight, survival days, and lung index of mice were recorded.

Regulation of Interferon-β-Modified Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes in Proliferation and Apoptosis of Prostate Cancer Cells

[Organogenesis] Prostate cancer were treated with exosomes (Exos). Cellular internalization of Exos by cells was detected by uptake assay.

Banked Term Umbilical Cord Blood to Meet the Packed Red Blood Cell Transfusion Needs of Extremely-Low-Gestational-Age Neonates: A Feasibility Analysis

[Journal Of Perinatology] Researchers retrospectively analyzed all ELGANs RBC Tx over the past three years, estimated local cord blood availability, and assesed interest in this project, and implementation barriers, through stakeholder surveys.

Placental Streptococcus agalactiae DNA Is Associated with Neonatal Unit Admission and Fetal Pro-Inflammatory Cytokines in Term Infants

[Nature Microbiology] The authors re-analyzed a dataset which detected Streptococcus agalactiae DNA in the placenta in ~5% of women before the onset of labour as a case control study of neonatal unit admission.

Stem Cell-Based Interventions for the Treatment of Stroke in Newborn Infants

[Cochrane Database Of Systematic Reviews] To evaluate the benefits and harms of stem cell‐based interventions for the treatment of stroke in newborn infants compared to control or stem‐cell based interventions of a different type or source.

Most Clinical Trials Run in Canada Failed to Take Basic Steps Toward Transparency, Analysis Finds

[STAT News] Just 3% of more than 3,700 studies run exclusively in Canada over a recent 10-year period were registered prospectively, reported results, and published the findings, underscoring ongoing concerns about clinical trial transparency, according to a new analysis.

Human Placental Extract Suppresses Mast Cell Activation and Induces Mast Cell Apoptosis

[Allergy Asthma And Clinical Immunology] To investigate the effects of HPE on the regulation of allergy with respect to the biological functions of mast cells, the mast cell line C57 or HMC-1 cells were treated with HPE followed by the assessment of cell proliferation, apoptosis, activation, chemotaxis and phagocytosis.

Cord Blood Stem Cell-Derived Angptl7 Ameliorates the Severity of Bronchopulmonary Dysplasia via Anti-Inflammatory and Proangiogenic Effects

[Molecular Medicine Reports] The authors compared Angptl7 levels between the autologous cord blood mononuclear cells infusion and control groups. Subsequently, the association between cord blood Angptl7 levels and bronchopulmonary dysplasia incidence in a cohort of very preterm neonates was assessed.

TNF-α and IFN-γ Prestimulation Enhances the Therapeutic Efficacy of Human Amniotic Epithelial Stem Cells in Chemotherapy-Induced Ovarian Dysfunction

[Inflammation And Regeneration] Investigators observed the pathological changes of the ovaries at different time points during chemotherapy, including the number of follicles, granulosa cell proliferation, oxidative stress damage, ovarian fibrosis, and inflammatory reaction.

Prenatal Hypertension As the Risk of Eclampsia, HELLP Syndrome, and Critical Obstetric Hemorrhage

[Hypertension Research] The authors clarified the impact of chronic hypertension on obstetric hemorrhage by evaluating a nationwide administrative database in Japan. Women who gave birth between 2018 and 2022 were enrolled.

Mitigation of Acute Radiation Syndrome (ARS) with Human Umbilical Cord Blood

[International Journal Of Radiation Biology] Scientists discuss acute radiation syndrom and its sub-syndromes, and to highlight recent findings regarding the use of umbilical cord blood for radiation injury.

Summarizing the latest research and reviews since 2009, Umbilical & Placental Cell News, previously known as Cord Blood News, keeps members of the scientific and medical community up-to-date on the latest discoveries and research publications related to cord blood stem cells, placental cells, amniotic fluid and membrane-derived cells, and all their derivatives. The publication serves as a valuable resource to keep scientists current with the latest clinical trials, policy updates, event postings, and career opportunities.