Muscle Cell News

Muscle Cell News is an online resource dedicated to the latest research into smooth, skeletal, and cardiac muscle cells.

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Foxk1 and Foxk2 Promote Cardiomyocyte Proliferation and Heart Regeneration

March 31, 2025

[Nature Communications] Researchers identified Foxk1 and Foxk2 as key regulators of cardiomyocyte proliferation, whose expression declines during postnatal heart development.

Vitamin A-Retinoic Acid Contributes to Muscle Stem Cell andMitochondrial Function Loss in Old Age

March 31, 2025

[JCI Insight] Investigators showed that Vitamin A, a micronutrient derived from diet and metabolized into retinoic acid, acted as an antioxidant and transcriptional regulator in muscle stem cells.

Zinc Finger Protein Znf296 Is a Cardiac-Specific Splicing Regulator Required for Cardiomyocyte Formation

March 31, 2025

[The American Journal of Pathology] The authors showed that ZNF296 regulated alternative splicing in human cardiomyocytes to maintain structural integrity.

HSPB1 Suppresses oxLDL-Induced Vascular Smooth Muscle Cell Ferroptosis by Inhibiting DPP4

March 31, 2025

[Archives of Biochemistry and Biophysics] Scientists revealed for the first time that heat shock protein B1 suppresses oxLDL-induced vascular smooth muscle cell ferroptosis by inhibiting DPP4 through NF-κB, which provides new strategies for the prevention and treatment of atherosclerosis.

Epsin Bioactive Coating Reduced In-Stent Intimal Hyperplasia by Promoting Early Phase Reendothelialization and Inhibiting Smooth Muscle Cell Proliferation

March 31, 2025

[PLOS One] Researchers suggested that Epsin plays a crucial role in endothelial and smooth muscle cell proliferation and migration functions, and its inhibition may be a potentially effective therapeutic strategy to prevent in stent stenosis.

Investigation of the Efficiency of Pulsed Electromagnetic Field Treatment and Stretching Exercise in Experimental Skeletal Muscle Injury Model

March 31, 2025

[BMC Musculoskeletal Disorders] Pulsed electromagnetic fields and stretching exercises are safe and noninvasive methods that could have a therapeutic effect on tissue healing. Researchers assessed the effectiveness of these methods in the treatment of muscle injury.

Cardiomyocyte Regeneration after Infarction: Changes, Opportunities, and Challenges

March 31, 2025

[Molecular and Cellular Biochemistry] The authors comprehensively describe the research progress of post-infarction cardiomyocyte regeneration, including the characteristics of cardiomyocytes and post-infarction changes, regeneration mechanisms, influencing factors, potential therapeutic strategies, challenges and future development directions, and deeply discusses the specific pathways and targets included in the regeneration mechanism.

Avidity Biosciences Completes Enrollment in Biomarker Cohort in Phase 1/2 FORTITUDE™ Trial for Delpacibart Braxlosiran (del-brax) in People Living with Facioscapulohumeral Muscular Dystrophy

March 31, 2025

[Avidity Biosciences, Inc.] Avidity Biosciences, Inc. announced the completion of enrollment in the biomarker cohort in the Phase I/II FORTITUDE™ clinical trial of delpacibart braxlosiran in people living with facioscapulohumeral muscular dystrophy.

Nanoparticle-Driven Skeletal Muscle Repair and Regeneration through Macrophage-Muscle Stem Cell Interaction

March 20, 2025

[Small] The authors synthesized lipoic acid-modified gold nanoparticles of varying sizes to evaluate their biocompatibility and immunomodulatory effects.

ZIP13 Marks Muscle Satellite Cells and Contributes to Their Quiescent and Active Phase Balance

March 19, 2025

[Scientific Reports] investigated Zip13-knockout (KO) mice and found a reduction in muscle satellite cells of Zip13-KO mice, in which the quiescent and activated phase balances were disrupted.

PLK1 Downregulation Attenuates ET-1-Induced Cardiomyocyte Hypertrophy by Suppressing the ERK1/2 Pathway

March 18, 2025

[Journal of Cardiovascular Translational Research] The authors found polo-like kinase 1 was crucial in regulating endothelin-1-induced cardiomyocyte hypertrophy.

Nrf3-Mediated Mitochondrial Superoxide Promotes Cardiomyocyte Apoptosis and Impairs Cardiac Functions by Suppressing Pitx2

March 18, 2025

[Circulation] Global and cardiomyocyte-specific Nrf3 knockout mice were subjected to myocardial infarction or ischemia/reperfusion injury, followed by functional and histopathological analysis.

Every day, our editorial team sifts through the most recent scientific literature to help keep researchers and medical professionals current. Muscle Cell News covers the three types of muscle cells: cardiac, skeletal, and smooth muscle. We cover a broad range of topics, including cell culturing, muscle regeneration, and musculoskeletal disorders.