Muscle Cell News

Muscle Cell News is an online resource dedicated to the latest research into smooth, skeletal, and cardiac muscle cells.

Adipocyte Plasticity in Tissue Regeneration, Repair, and Disease

[Current Opinion in Genetics & Development] The author discusses the plasticity and function of adipocytes to tissue repair and fibrosis in four tissues: skin, heart, skeletal muscle, and mammary gland.

Baylor College of Medicine Recognizes Research Excellence with DeBakey Awards

[Baylor College of Medicine] Each year, Baylor College of Medicine faculty are recognized for their outstanding published scientific contributions to clinical and basic science research over the past three years through the Michael E. DeBakey MD Award for Excellence in Research.

Muscle Degeneration in Chronic Massive Rotator Cuff Tears of the Shoulder: Addressing the Real Problem Using a Graphene Matrix

[Proceedings of the National Academy of Sciences of the United States of America] Researchers established understandings on the effects of graphene nanoplatelets matrices on muscle regeneration and inhibition of fat formation in vitro and the ability of GnP matrices to reverse muscle degenerative changes in vivo following an massive rotator cuff tears.

Transcription Factor GATA4 Regulates Cell Type–Specific Splicing Through Direct Interaction with RNA in Human Induced Pluripotent Stem Cell–Derived Cardiac Progenitors

[Circulation] The authors found that GATA4 interacted with many members of the spliceosome complex in human induced pluripotent stem cell–derived cardiac progenitors.

Nitrite Lowers the Oxygen Cost of ATP Supply in Cultured Skeletal Muscle Cells by Stimulating the Rate of Glycolytic ATP Synthesis

[PLoS One] The authors reported the acute effects of sodium nitrite on the bioenergetic behaviour of cultured rat myocytes.

Sex-Dependent Role of Pannexin 1 in Regulating Skeletal Muscle and Satellite Cell Function

[Journal of Cellular Physiology] Using global Panx1 knockout mice, scientists demonstrated that Panx1 loss reduced muscle fiber size and strength, decreased satellite cell (SC) number, and altered early SC differentiation and myoblast fusion in male, but not in female mice.

Functional Human Cell-Based Vascularized Cardiac Tissue Model for Biomedical Research and Testing

[Scientific Reports] To improve the maturity and physiological relevance of hiPSC-derived cardiomyocytes, scientists co-cultured them with preconstructed vascular-like networks to form a functional, human cell-based cardiac tissue model.

Fibroblast-Derived Exosomal miRNA-133 Promotes Cardiomyocyte-Like Differentiation

[Acta Histochemica] Researchers investigated the role of exosomal miRNA-133 secreted by cardiac fibroblasts in promoting cardiomyocyte differentiation.

The Complicated Lives of GPCRs in Cardiac Fibroblasts

[American Journal of Physiology-Cell Physiology] The authors reviewed on the relatively less well studied effects of G protein-coupled receptors (GPCRs) in cardiac fibroblasts, focusing on key signalling events involved in the activation and differentiation of these cells.

Physiological Calcium Combined with Electrical Pacing Accelerates Maturation of Human Engineered Heart Tissue

[Stem Cell Reports] Investigators presented a method whereby maturation of human iinducedPSC-CMs can be accelerated by simultaneous application of physiological Ca2+ and frequency-ramped electrical pacing in culture.

Hypoxia-Induced miR-182-5p Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Targeting RGS5

[Cell Biology International] Researchers investigated the function of miR-182-5p in vascular smooth muscle cells phenotypic switch.

Thoracic Perivascular Adipose Tissue Inhibits VSMC Apoptosis and Aortic Aneurysm Formation in Mice via the Secretome of Browning Adipocytes

[Acta Pharmacologica Sinica] Scientists investigated the effect of thoracic PVAT (T-PVAT) transplantation on aortic aneurysm formation and the impact of T-PVAT on vascular smooth muscle cells.

Every day, our editorial team sifts through the most recent scientific literature to help keep researchers and medical professionals current. Muscle Cell News covers the three types of muscle cells: cardiac, skeletal, and smooth muscle. We cover a broad range of topics, including cell culturing, muscle regeneration, and musculoskeletal disorders.