Pancreatic Cell News

Pancreatic Cell News is an online resource providing updates on the latest pancreatitis, diabetes, and pancreatic cancer research.

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UBC Medicine Researchers Awarded More Than $39 Million in CIHR Funding

August 17, 2026

[The University of British Columbia] UBC Faculty of Medicine researchers have been awarded more than $39 million in federal funding through the Canadian Institutes of Health Research (CIHR) Project Grant: Spring 2026 competition.

$1 Million Grant Fuels Research on Precise Cancer Radiation

August 14, 2026

[University of Missouri School of Medicine] Researchers from the University of Missouri School of Medicine recently received a $1 million grant from the National Institutes of Health to study the latest technology in cancer research.

Metabolic Reprogramming Drives Pancreatic β Cell Neogenesis from α Cells

August 11, 2026

[Nature Chemical Biology] Researchers identified PRC2 inhibitors as potent inducers of β cell-enriched gene expression in α cells, acting through modulation of the AR–ETV1 complex.

Adipose Tissue Palmitoylation Cycling Mediates Insulin Resistance and Preservation of β Cell Function in Mice

August 11, 2026

[Diabetes] Investigators showed that adipose tissue palmitoylation cycling helps preserve pancreatic β-cell function and insulin secretion despite sustained insulin resistance.

RNA Methyltransferase 3 Drives Pancreatic Acinar Cell Carcinoma Growth and Is a Therapeutic Target

August 11, 2026

[Signal Transduction and Targeted Therapy] The authors investigated the role of methyltransferase 3-mediated RNA methylation in pancreatic acinar cell carcinoma development and progression.

Targeting the αVβ5 Integrin Modifies the TGFβ-Rich Tumor Microenvironment of Pancreatic Cancer

August 11, 2026

[Cancer Research] Scientists demonstrated that the αv integrin and neuropilin-1 dual targeting iRGD peptide reverses some of these tumor microenvironment features by inhibiting transforming growth factor β (TGFβ) activation in the tumor, a process mediated by the αvβ5 integrin.

Discovery of Pyrazole Derivative IHMT-140 As a Pancreatic Cancer Therapeutic Agent via Dual Mechanisms DDR1 Inhibition and Methuosis Induction

August 11, 2026

[Journal of Advanced Research] Researchers identified a small molecule as a therapeutic agent for pancreatic cancer through dual mechanisms, specifically Discoidin domain receptor 1 (DDR1) inhibition and methuosis induction.

Targeting CCR1 Remodels the Tumor Microenvironment and Relieves Immunosuppression in Pancreatic Cancer

August 11, 2026

[Cancer Immunology Research] Investigators showed that targeting C-C motif chemokine receptor 1 (CCR1) remodels the pancreatic tumor microenvironment, reducing myeloid-driven immunosuppression and enhancing CD8+ T-cell activity and immunotherapy response.

Lysosomal Metabolism in Pancreatic Cancer and Its Crosstalk with Host Physiology

August 11, 2026

[Genes & Development] Scientists highlight lysosomal metabolism as a key survival mechanism in pancreatic cancer, linking nutrient recycling, tumor–host crosstalk, and immune evasion to potential therapeutic vulnerabilities.

$2 Million NCI Grant Funds Research on How Pancreatic Cancer Uses Cholesterol to Survive

August 11, 2026

[University of Oklahoma] A University of Oklahoma researcher has received a five-year, $2 million grant from the National Cancer Institute to investigate how pancreatic cancer uses cholesterol to survive chemotherapy.

Differential Mirroring Between In Vivo Insulin Secretion and Ex Vivo Islet Function in Individuals with and Without Diabetes

July 27, 2026

[Metabolism Clinical and Experimental] Researchers studied 63 individuals undergoing partial pancreatectomy who underwent preoperative OGTT with model-based assessment of β cell function and provided pancreatic tissue for ex vivo islet isolation and glucose stimulation.

3D Epigenomic Remodelling Mediated by Foxa1 Drives Gemcitabine Resistance in Pancreatic Cancer

July 27, 2026

[Cancer Letters] Scientists established Foxa1-orchestrated enhancer reprogramming as a fundamental mechanism of gemcitabine resistance and unveil a promising epigenetic therapy to restore treatment efficacy in PDAC.

Pancreatic Cell News highlights recent top articles in the field of pancreatic cell research. These articles have been carefully selected from high-impact, peer-reviewed academic journals by our experienced editorial team. We cover topics including pancreatic cell culture, pancreatitis, diabetes, and pancreatic cancer. We also feature the latest industry and policy news alongside job postings and upcoming events to keep scientists current while saving them valuable time.