PAFAH1B3 Is a KLF9 Target Gene that Promotes Proliferation and Metastasis in Pancreatic Cancer

Researchers found that platelet-activating factor acetylhydrolase IB3 (PAFAH1B3) was highly expressed in pancreatic cancer tissues and cells. In vitro and in vivo studies showed that overexpression of PAFAH1B3 promoted the proliferation and invasion of pancreatic cancer cells, while downregulation of PAFAH1B3 inhibited these processes.