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Muscle Cell News
NOR-1 Overexpression Elevates Myoglobin Expression via PERM1 and Enhances Mitochondrial Function and Endurance in Skeletal Muscles of Aged Mice
[FASEB Journal] Transcriptomic profiling of the human response to exercise revealed that the nuclear receptor NR4A3 (NOR-1) was among the most responsive genes to acute exercise.
Muscle Cell News
One-Step Laser-Assisted Electrohydrodynamic Printing of Microelectronic Scaffolds for Electrophysiological Monitoring of Aligned Cardiomyocytes
[ACS Nano ] A laser-assisted electrohydrodynamic printing strategy was proposed to directly fabricate a microfibrous architecture with built-in microelectronics for electrophysiological monitoring of aligned cardiomyocytes.
Muscle Cell News
Sarcopenia and Skeletal Muscle Loss after CAR T-cell Therapy in Diffuse Large B cell Lymphoma
[Clinical Cancer Research] In 83 large B-cell lymphoma patients, the skeletal muscle index was measured from clinical images obtained at baseline and days 30 and 90 post-therapy.
Hepatic Cell News
Pregnane X Receptor Alleviates Sepsis-Induced Liver Injury through Activation of Yes-Associated Protein in Mice
[Acta Pharmacologica Sinica] Scientists investigated the role of pregnane X receptor in sepsis-induced liver injury and the underlying mechanisms.
Hepatic Cell News
Chronic Intermittent Hypoxia Alleviates Alcohol-Related Liver Injury via Downregulation of Hepatic Hypoxia-Inducible Factor-2α
[American Journal of Physiology-Gastrointestinal and Liver Physiology] As an approach to investigate the relationship between alcohol-enhanced obstructive sleep apnea and alcohol-related liver disease (ALD) development/progression in vivo Gao-binge ALD and chronic intermittent hypoxia mouse models were established.
Hepatic Cell News
Integrated Liver-Secreted and Plasma Proteomics Identify a Predictive Model That Stratifies MASH
[Cell Reports Medicine] Researchers assessed plasma and liver from 266 obese individuals spanning the metabolic-associated steatotic liver disease spectrum. Ninety-six human livers were precision-cut, and mass spectrometry-based proteomics identified 3,333 proteins in the liver-secretion medium, of which 107 were differentially secreted in metabolic-associated steatohepatitis (MASH) compared with no pathology.