Scientists used an adeno-associated viral (AAV) vector to express a dominant-negative form of ULK1 and investigated its effects on axonal regeneration in the central nervous system.
[Cell Death & Disease]
Ribas, V. T., Vahsen, B. F., Tatenhorst, L., Estrada, V., Dambeck, V., Almeida, R. A., Bähr, M., Michel, U., Koch, J. C., Müller, H. W., & Lingor, P. (2021). AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo. Cell Death & Disease, 12(2), 1–18. https://doi.org/10.1038/s41419-021-03503-3 Cite
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