Publication

[International Journal of Oral Science] Scientists revealed that loss of Gli3 alone in dental mesenchymal root progenitor cells caused shortened roots and that concurrent loss of Gli2 and Gli3 exacerbated root malformations, concomitant with profound impairments in cell proliferation and multilineage differentiation.

[Advanced Healthcare Materials] Researchers transfected bone MSCs with RUNX2 plasmid nanoparticles and encapsulated them into gelatin methacryloyl hydrogel microcarriers for bone regeneration.

[Stem Cell Research & Therapy] Investigators constructed endothelial progenitor cells/peripheral blood derived-MSCs sheets and evaluated their repair value and potential molecular mechanisms in bone regeneration.

[Biology Direct] Scientists integrated human umbilical cord MSCs into single-source liver organoids and assessed their effects on organoid formation and function.

[Biomacromolecules] Researchers developed poly(ethylene glycol)-derived hydrogels cross-linked with QAT-functionalized macromers. The cytocompatibility of the cross-linking was demonstrated by gelation in the presence of MESCNs and sustained cell viability.

[ACS Biomaterials Science & Engineering] Investigators elucidate the molecular mechanism by which the natural compound apigenin regulates osteoporosis-bone marrow MSCs, and its pharmacokinetic limitations are addressed with a smart delivery system, collectively offering a new strategy for the precise treatment of osteoporosis.