Pulmonary Cell News

Pulmonary Cell News is an online resource dedicated to the topics of respiratory disease, lung cancer, and pulmonary cells.

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$1 Million Grant Fuels Research on Precise Cancer Radiation

August 14, 2026

[University of Missouri School of Medicine] Researchers from the University of Missouri School of Medicine recently received a $1 million grant from the National Institutes of Health to study the latest technology in cancer research.

BCL9 Inhibition Promotes Fibroblast Lipogenesis by Regulating Macrophage-Fibroblast Interactions to Attenuate Pulmonary Fibrosis

August 13, 2026

[Signal Transduction and Targeted Therapy] Scientists identified B cell lymphoma 9 (BCL9) as a key upstream regulator implicated in idiopathic pulmonary fibrosis pathogenesis. They demonstrated that BCL9 drives the macrophage M2 program through the MerTK-ERK-SPP1 axis.

Pulmonary Delivery of Self-Amplifying RNA: Balancing Inflammation and Durable Transgene Expression

August 13, 2026

[ACS Nano] The authors demonstrated that intratracheal administration of self-amplifying mRNA-lipid nanoparticles can cause significant side effects that can be linked to innate immune cell recruitment and cytokine release in the lungs.

Amiloride Mitigates Respiratory Distress Caused by WFDC2 Deficiency via Inhibiting the Epithelial Sodium Channel

August 13, 2026

[Nature Communications] Investigators explored the p.C97W variant in WAP four-disulfide core domain protein 2 (WFDC2), proposed as a new genetic origin of respiratory distress.

Biomarkers of Nivolumab Benefit in Resectable Non-Small Cell Lung Cancer

August 13, 2026

[Nature] Researchers identify circulating tumor DNA clearance and molecular residual disease as key biomarkers of nivolumab benefit and recurrence risk in resectable non-small cell lung cancer.

MPND Loss Epigenetically Activates TGFβ/SMAD3 Signaling to Drive Tumor Progression and Metastasis in Non-Small Cell Lung Cancer

August 13, 2026

[Cancer Research] Scientists found that Mpr1/Pad1 N-terminal domain-containing protein (MPND) is frequently deleted, and its expression is significantly downregulated in NSCLC tumor tissues.

Hypoxia-Induced MIC19 Myristoylation Promotes PRKN-Dependent VDAC2 Ubiquitination and Activates Mitophagy in Non-Small Cell Lung Cancer

August 13, 2026

[Oncogene] Researchers dentified MIC19, a key subunit of mitochondrial contact site and cristae organizing system complex, as an essential regulator of hypoxia-induced mitophagy in NSCLC.

VHH-Based CAR-T Cells Targeting DLL3 Show High Efficacy in Small Cell Lung Cancer Models

August 13, 2026

[Molecular Cancer Therapeutics] Investigators showed that DLL3-targeting variable domain of heavy-chain–only antibodies (VHH)-based chimeric antigen receptor T (CAR-T) cells exhibit potent antitumor activity against small cell lung cancer, supporting their potential as a new immunotherapy for DLL3-positive tumors.

Fucosyltransferases in Asthma: Regulators of Epithelial Dysfunction, Senescence, and Airway Inflammation

August 13, 2026

[Clinical Reviews in Allergy & Immunology] Scientists summarize the current knowledge of the fucosyltransferase family and critically evaluate the evidence linking aberrant fucosylation to asthma pathogenesis.

UCLA Researchers Receive $1.2 Million to Study Diabetes Drug As a Potential Treatment for Early-Stage Lung Cancer

August 13, 2026

[UCLA Health] UCLA researchers received a $1.2 million grant to investigate whether a common diabetes drug could slow early-stage lung adenocarcinoma and help prevent future lung cancers.

UToledo Research Receives Funding from Stand Up To Cancer to Test Early Warning for Lung Cancer

August 13, 2026

[University of Toledo] Dr. James Willey, a pulmonary physician at University of Toledo (UToledo) Health and holder of the George Isaac Chair In Cancer Research, has received a $200,000 Stand Up To Cancer grant to support a simple, noninvasive screening test for lung cancer.

ADAMTS14 Is a Novel Modulator of Fibroblast Mechanoactivation in Pulmonary Fibrosis

July 30, 2026

[American Journal of Respiratory and Critical Care Medicine] Investigators characterized the role of ADAM with Thrombospondin motifs 14 (ADAMTS14) in YAP-mediated fibroblast mechanoactivation and pulmonary fibrosis.

Spurred by advances in the modeling of the airway epithelium, Pulmonary Cell News was launched in 2012 to help scientists stay at the forefront of cutting edge research. Every week, our editors hand-select the most recent, top scientific journal articles on the topics of pulmonary cells, lung cancers, and respiratory diseases such as COPD and asthma. We also highlight current job postings and upcoming events to keep the global research community connected!