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CHIP-Overexpressing Wharton’s Jelly-Derived Mesenchymal Stem Cells Attenuate Hyperglycemia-Induced Oxidative Stress-Mediated Kidney Injuries in Diabetic Rats

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Western blot analysis, flow cytometry, and MitoSOX staining revealed that hyperglycemia-induced mitochondrial oxidative stress production and apoptosis were attenuated in CHIP-overexpressing Wharton’s jelly-derived mesenchymal stem cells
[Free Radical Biology and Medicine]
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Ali, A., Shibu, M. A., Kuo, C.-H., Lo, J.-F., Chen, R.-J., Day, C. H., Ho, T.-J., PadmaViswanadha, V., Kuo, W.-W., & Huang, C.-Y. (2021). CHIP-overexpressing Wharton’s jelly-derived mesenchymal stem cells attenuate hyperglycemia-induced oxidative stress-mediated kidney injuries in diabetic rats. Free Radical Biology and Medicine, 173, 70–80. https://doi.org/10.1016/j.freeradbiomed.2021.07.026 Cite
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