Investigators found that knockout of Mst1 and Mst2, two key components of the Hippo signaling in mouse ESCs, resulted in a disruption of differentiation into mesendoderm lineage. They revealed a novel mechanism on how the Hippo-YAP signaling pathway dictated ESC lineage differentiation.
[Nucleic Acids Research]
6445212
{6630899:XAJQUHEJ}
apa
50
1
150626
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