Scientists showed that Itgav deletion results in increased frequency of phenotypic hematopoietic stem cells in fetal liver due to faster proliferation.
[Stem Cell Reports]
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Biswas, A., Roy, I. M., Babu, P. C., Manesia, J., Schouteden, S., Vijayakurup, V., Anto, R. J., Huelsken, J., Lacy-Hulbert, A., Verfaillie, C. M., & Khurana, S. (2020). The Periostin/Integrin-αv Axis Regulates the Size of Hematopoietic Stem Cell Pool in the Fetal Liver. Stem Cell Reports, 0(0). https://doi.org/10.1016/j.stemcr.2020.06.022 Cite
