DEFA5 directly bound with BMI‐1, which subsequently decreased its binding at the CDKN2a locus and upregulated the expression of two cyclin‐dependent kinase inhibitors, p16 and p19.
[Cancer Science]
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The inhibitory Effect of human DEFA5 in Growth of gastric cancer by targeting BMI‐1 - Wu - - Cancer Science - Wiley Online Library. (n.d.). Retrieved January 28, 2021, from https://onlinelibrary.wiley.com/doi/10.1111/cas.14827 Cite
