Scientists developed a novel electrochemical sensing approach capable of detecting dopamine, the main biomarker in Parkinson’s disease, within the highly complex cell culture matrix of human midbrain organoids in a non-invasive and label-free manner.
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Zanetti, C., Spitz, S., Berger, E., Bolognin, S., Smits, L. M., Crepaz, P., Rothbauer, M., Rosser, J. M., Marchetti-Deschmann, M., Schwamborn, J. C., & Ertl, P. (2021). Monitoring the neurotransmitter release of human midbrain organoids using a redox cycling microsensor as a novel tool for personalized Parkinson’s disease modelling and drug screening. Analyst. https://doi.org/10.1039/D0AN02206C Cite
