The authors describe a cellular contractile mechanism employed by fibroblasts and mesenchymal cancer cells to migrate in 3D collagen gels.
[Developmental Cell]
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Doyle, A. D., Sykora, D. J., Pacheco, G. G., Kutys, M. L., & Yamada, K. M. (2021). 3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain. Developmental Cell, 0(0). https://doi.org/10.1016/j.devcel.2021.02.017 Cite
