Researchers revealed that periarteriolar bone marrow-resident NG2+/Nestin+ mesenchymal stem cells can also instruct breast cancer disseminated tumor cells to enter dormancy.
[Nature Cancer]
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Nobre, A. R., Risson, E., Singh, D. K., Di Martino, J. S., Cheung, J. F., Wang, J., Johnson, J., Russnes, H. G., Bravo-Cordero, J. J., Birbrair, A., Naume, B., Azhar, M., Frenette, P. S., & Aguirre-Ghiso, J. A. (2021). Bone marrow NG2 + /Nestin + mesenchymal stem cells drive DTC dormancy via TGF-β2. Nature Cancer, 1–13. https://doi.org/10.1038/s43018-021-00179-8 Cite
