Investigators revealed that the epicardium and pericardium-derived Semaphorin 3E and its receptor, PlexinD1, played a role in the development of the coronary stem, as well as cardiac lymphatic vessels.
[iScience]
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Maruyama, K., Naemura, K., Arima, Y., Uchijima, Y., Nagao, H., Yoshihara, K., Singh, M. K., Uemura, A., Matsuzaki, F., Yoshida, Y., Kurihara, Y., Miyagawa-Tomita, S., & Kurihara, H. (2021). Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. IScience, 0(0). https://doi.org/10.1016/j.isci.2021.102305 Cite
