Researchers showed that glial fibrillary acidic protein (GFAP) was readily palmitoylated in vitro and in vivo; specifically, cysteine-291 was the unique palmitoylated residue in GFAP.
[Proceedings of the National Academy of Sciences of the United States of America]
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Yuan, W., Lu, L., Rao, M., Huang, Y., Liu, C., Liu, S., Zhao, Y., Liu, H., Zhu, J., Chao, T., Wu, C., Ren, J., Lv, L., Li, W., Qi, S., Liang, Y., Yue, S., Gao, J., Zhang, Z., & Kong, E. (2021). GFAP hyperpalmitoylation exacerbates astrogliosis and neurodegenerative pathology in PPT1-deficient mice. Proceedings of the National Academy of Sciences, 118(13). https://doi.org/10.1073/pnas.2022261118 Cite
