Transplantation of the hiPSC-derived neural crest cells rapidly restored rabbit corneal thickness and clarity. However, the long-term recovery efficacy was impaired by the improper maturation, senescence, and endothelial-mesenchymal transition of the transplanted cells.
[Stem Cell Research & Therapy]
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Gong, Y., Duan, H., Wang, X., Zhao, C., Li, W., Dong, C., Li, Z., & Zhou, Q. (2021). Transplantation of human induced pluripotent stem cell-derived neural crest cells for corneal endothelial regeneration. Stem Cell Research & Therapy, 12(1), 214. https://doi.org/10.1186/s13287-021-02267-z Cite
