The authors proposed that in addition to ataxia‐telangiectasia and Rad3 related (ATR), a MYBL2‐MRN‐ATM replication stress response pathway functioned in ESCs to control DNA replication initiation and prevent genome instability.
[EMBO Reports]
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Blakemore, D., Vilaplana-Lopera, N., Almaghrabi, R., Gonzalez, E., Moya, M., Ward, C., Murphy, G., Gambus, A., Petermann, E., Stewart, G. S., & García, P. (2021). MYBL2 and ATM suppress replication stress in pluripotent stem cells. EMBO Reports, n/a(n/a), e51120. https://doi.org/10.15252/embr.202051120 Cite
