Researchers showed that UDP-glucose, a nucleotide sugar, was selectively released into the airways of allergen-sensitized mice upon their subsequent challenge with that same allergen.
[Journal of Clinical Investigation]
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Karcz, T. P., Whitehead, G. S., Nakano, K., Nakano, H., Grimm, S. A., Williams, J. G., Deterding, L. J., Jacobson, K. A., & Cook, D. N. (2021). UDP-glucose and P2Y14 receptor amplify allergen-induced airway eosinophilia. The Journal of Clinical Investigation, 131(7). https://doi.org/10.1172/JCI140709 Cite
