Scientists characterized innate immune responses of human and murine colonoids to bacteria and host products and the role of IL-37/SIGIRR in regulating these responses.
[Scientific Reports]
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Allaire, J. M., Poon, A., Crowley, S. M., Han, X., Sharafian, Z., Moore, N., Stahl, M., Bressler, B., Lavoie, P. M., Jacobson, K., Li, X., & Vallance, B. A. (2021). Interleukin-37 regulates innate immune signaling in human and mouse colonic organoids. Scientific Reports, 11(1), 8206. https://doi.org/10.1038/s41598-021-87592-2 Cite
