Investigators utilized a neonatal rat model of bronchopulmonary dysplasia to assess if hyperoxia stimulates lung release of circulating extracellular vesicles(EVs) and if these EVs induce lung and brain injury.
[Scientific Reports]
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Ali, A., Zambrano, R., Duncan, M. R., Chen, S., Luo, S., Yuan, H., Chen, P., Benny, M., Schmidt, A., Young, K., Kerr, N., de Rivero Vaccari, J. P., Keane, R. W., Dietrich, W. D., & Wu, S. (2021). Hyperoxia-activated circulating extracellular vesicles induce lung and brain injury in neonatal rats. Scientific Reports, 11(1), 8791. https://doi.org/10.1038/s41598-021-87706-w Cite
