Researchers found that upper stratum granulosum cell death was preceded by prolonged (∼60 min) Ca2+ elevation and rapid induction of intracellular acidification.
[Proceedings of the National Academy of Sciences of the United States of America]
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Matsui, T., Kadono-Maekubo, N., Suzuki, Y., Furuichi, Y., Shiraga, K., Sasaki, H., Ishida, A., Takahashi, S., Okada, T., Toyooka, K., Sharif, J., Abe, T., Kiyonari, H., Tominaga, M., Miyawaki, A., & Amagai, M. (2021). A unique mode of keratinocyte death requires intracellular acidification. Proceedings of the National Academy of Sciences, 118(17). https://doi.org/10.1073/pnas.2020722118 Cite
