Investigators demonstrated that miR-3140-3p suppresses tumor cell growth in MYCN-amplified NB by downregulating MYCN and MYC through BRD4 suppression.
[Molecular Therapy-Nucleic Acids]
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Liu, C., Gen, Y., Tanimoto, K., Muramatsu, T., Inoue, J., & Inazawa, J. (2021). Concurrent targeting of MAP3K3 and BRD4 by miR-3140-3p overcomes acquired resistance to BET inhibitors in neuroblastoma cells. Molecular Therapy - Nucleic Acids, 0(0). https://doi.org/10.1016/j.omtn.2021.05.001 Cite
