Using a novel screening method, investigators identified novel transcription factors that regulated the intestinal stem cell fate upon endoplasmic reticulum stress.
[Scientific Reports]
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Meijer, B. J., Smit, W. L., Koelink, P. J., Westendorp, B. F., de Boer, R. J., van der Meer, J. H. M., Vermeulen, J. L. M., Paton, J. C., Paton, A. W., Qin, J., Dekker, E., Muncan, V., van den Brink, G. R., & Heijmans, J. (2021). Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2. Scientific Reports, 11(1), 9892. https://doi.org/10.1038/s41598-021-89326-w Cite
