we found that YTHDF2 was significantly upregulated in Lung adenocarcinoma (LUAD) compared with paracancerous normal tissues, and YTHDF2 knockdown drastically inhibited, while its overexpression promoted, cell growth, colony formation and migration of LUAD cells in vitro.
[Cell Death & Disease]
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Li, Y., Sheng, H., Ma, F., Wu, Q., Huang, J., Chen, Q., Sheng, L., Zhu, X., Zhu, X., & Xu, M. (2021). RNA m 6 A reader YTHDF2 facilitates lung adenocarcinoma cell proliferation and metastasis by targeting the AXIN1/Wnt/β-catenin signaling. Cell Death & Disease, 12(5), 1–14. https://doi.org/10.1038/s41419-021-03763-z Cite
