Researchers reported that targeting neuropilin 2 (NRP2) in cancer cells could enhance taxane-based chemotherapy with a better therapeutic outcome in bone metastasis, implicating NRP2 as a promising therapeutic target.
[Bone Research]
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Polavaram, N. S., Dutta, S., Islam, R., Bag, A. K., Roy, S., Poitz, D., Karnes, J., Hofbauer, L. C., Kohli, M., Costello, B. A., Jimenez, R., Batra, S. K., Teply, B. A., Muders, M. H., & Datta, K. (2021). Tumor- and osteoclast-derived NRP2 in prostate cancer bone metastases. Bone Research, 9(1), 1–16. https://doi.org/10.1038/s41413-021-00136-2 Cite
