Researchers show that Nav1.8+ sensory neurons, which are involved in pain perception, control the magnitude of CD8 T cell priming and expansion in HSV-1-infected mice.
[Nature Communications]
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Filtjens, J., Roger, A., Quatrini, L., Wieduwild, E., Gouilly, J., Hoeffel, G., Rossignol, R., Daher, C., Debroas, G., Henri, S., Jones, C. M., Malissen, B., Mackay, L. K., Moqrich, A., Carbone, F. R., & Ugolini, S. (2021). Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection. Nature Communications, 12(1), 2936. https://doi.org/10.1038/s41467-021-22841-6 Cite
