Researchers reported CD109/STAT3 axis as crucial for the maintenance of stemness and tumorigenicity of glioma stem cells and as a mediator of chemoresistance.
[JCI Insight]
7753456
{7753456:2VIDNMRQ}
apa
50
1
162405
https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-435875fe55c21570e2f3692026c8fe72%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%222VIDNMRQ%22%2C%22library%22%3A%7B%22id%22%3A7753456%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Filppu%20et%20al.%22%2C%22parsedDate%22%3A%222021-05-10%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFilppu%2C%20P.%2C%20Ramanathan%2C%20J.%20T.%2C%20Granberg%2C%20K.%20J.%2C%20Gucciardo%2C%20E.%2C%20Haapasalo%2C%20H.%2C%20Lehti%2C%20K.%2C%20Nykter%2C%20M.%2C%20Joncour%2C%20V.%20L.%2C%20%26amp%3B%20Laakkonen%2C%20P.%20%282021%29.%20CD109-GP130%20interaction%20drives%20glioblastoma%20stem%20cell%20plasticity%20and%20chemoresistance%20through%20STAT3%20activity.%20%3Ci%3EJCI%20Insight%3C%5C%2Fi%3E%2C%20%3Ci%3E6%3C%5C%2Fi%3E%289%29.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1172%5C%2Fjci.insight.141486%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1172%5C%2Fjci.insight.141486%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D7753456%26amp%3Bitem_key%3D2VIDNMRQ%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22CD109-GP130%20interaction%20drives%20glioblastoma%20stem%20cell%20plasticity%20and%20chemoresistance%20through%20STAT3%20activity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pauliina%22%2C%22lastName%22%3A%22Filppu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jayendrakishore%20Tanjore%22%2C%22lastName%22%3A%22Ramanathan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kirsi%20J.%22%2C%22lastName%22%3A%22Granberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Erika%22%2C%22lastName%22%3A%22Gucciardo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hannu%22%2C%22lastName%22%3A%22Haapasalo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kaisa%22%2C%22lastName%22%3A%22Lehti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matti%22%2C%22lastName%22%3A%22Nykter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vadim%20Le%22%2C%22lastName%22%3A%22Joncour%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pirjo%22%2C%22lastName%22%3A%22Laakkonen%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021%5C%2F05%5C%2F10%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1172%5C%2Fjci.insight.141486%22%2C%22ISSN%22%3A%220021-9738%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Finsight.jci.org%5C%2Farticles%5C%2Fview%5C%2F141486%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%22TUURQW3H%22%5D%2C%22dateModified%22%3A%222021-05-14T18%3A56%3A11Z%22%7D%7D%5D%7D
Filppu, P., Ramanathan, J. T., Granberg, K. J., Gucciardo, E., Haapasalo, H., Lehti, K., Nykter, M., Joncour, V. L., & Laakkonen, P. (2021). CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity. JCI Insight, 6(9). https://doi.org/10.1172/jci.insight.141486 Cite
