Liquid chromatography with tandem mass spectrometry was used to analyze epoxyeicosatrienoic acids (EETs) in the lung tissues of patients with idiopathic pulmonary fibrosis and controls, and the function of 11,12-EET was evaluated in in vitro and in vivo in pulmonary fibrosis models.
[Environmental & Molecular Medicine]
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Kim, H. S., Moon, S.-J., Lee, S. E., Hwang, G. W., Yoo, H. J., & Song, J. W. (2021). The arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis. Experimental & Molecular Medicine, 1–11. https://doi.org/10.1038/s12276-021-00618-7 Cite
