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Synergistic Cycles of Protease Activity and Inflammation via PPARγ Degradation in Chronic Obstructive Pulmonary Disease

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Scientists evaluated the effect of neutrophil elastase on lipopolysaccharide – induced interleukin 8 production and determined the molecular mechanism in human bronchial epithelial cells.
[Experimental and Molecular Medicine]
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Kwak, N., Lee, K.-H., Woo, J., Kim, J., Lee, C.-H., & Yoo, C.-G. (2021). Synergistic cycles of protease activity and inflammation via PPARγ degradation in chronic obstructive pulmonary disease. Experimental & Molecular Medicine, 1–9. https://doi.org/10.1038/s12276-021-00626-7 Cite
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