In each bladder cancer organoid strain, epidermal growth factor receptor/ERK signaling was upregulated compared with normal bladder cells.
[Cancer Biology & Therapy]
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Elbadawy, M., Sato, Y., Mori, T., Goto, Y., Hayashi, K., Yamanaka, M., Azakami, D., Uchide, T., Fukushima, R., Yoshida, T., Shibutani, M., Kobayashi, M., Shinohara, Y., Abugomaa, A., Kaneda, M., Yamawaki, H., Usui, T., & Sasaki, K. (2021). Anti-tumor effect of trametinib in bladder cancer organoid and the underlying mechanism. Cancer Biology & Therapy, 0(0), 1–15. https://doi.org/10.1080/15384047.2021.1919004 Cite
