Researchers assessed the influence of culture duration on the relative proteome abundance of HepG2 cells cultured as spheroids, which are routinely used to model aspects of the liver.
[Scientific Reports]
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Ellero, A. A., van den Bout, I., Vlok, M., Cromarty, A. D., & Hurrell, T. (2021). Continual proteomic divergence of HepG2 cells as a consequence of long-term spheroid culture. Scientific Reports, 11(1), 10917. https://doi.org/10.1038/s41598-021-89907-9 Cite
