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Translational Shutdown and Evasion of the Innate Immune Response by SARS-CoV-2 NSP14 Protein

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Scientists showed that the translation inhibition activity of NSP14 was conserved in human coronaviruses. NSP14 was required for virus replication through contribution of its exoribonuclease and N7-methyltransferase activities.
[Proceedings of the National Academy of Sciences of the United States of America]

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