Utilizing Min6 cells, a pancreatic ß-cell model, scientists knocked down G-protein coupled receptor kinase 2 (GRK2) and measured glucose-mediated intracellular calcium responses and insulin secretion.
[Scientific Reports]
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Snyder, J., Lackey, A. I., Brown, G. S., Diaz, M., Yuzhen, T., & Sato, P. Y. (2021). GRK2 contributes to glucose mediated calcium responses and insulin secretion in pancreatic islet cells. Scientific Reports, 11(1), 11129. https://doi.org/10.1038/s41598-021-90253-z Cite
