Home Newsletters ESC & iPSC News Cellular Reprogramming of Diabetic Foot Ulcer Fibroblasts Triggers Pro-healing miRNA-Mediated Epigenetic Signature

Cellular Reprogramming of Diabetic Foot Ulcer Fibroblasts Triggers Pro-healing miRNA-Mediated Epigenetic Signature

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Investigators found that let-7c, miR-26b-5p, −29c-3p, −148a-3p, −196a-5p, −199b-5p and −374a-5p were suppressed in iPSC-derived fibroblasts in vitro and in 3D dermis-like self-assembly tissue, whereas their corresponding targets involved in cellular migration were upregulated.
[Experimental Dermatology]

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Abstract
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