Investigators utilized human induced pluripotent stem cells to generate reproducible organoids that recapitulate dorsal forebrain development including early corticogenesis.
[Molecular Psychiatry]
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Notaras, M., Lodhi, A., Barrio-Alonso, E., Foord, C., Rodrick, T., Jones, D., Fang, H., Greening, D., & Colak, D. (2021). Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids. Molecular Psychiatry, 1–24. https://doi.org/10.1038/s41380-021-01189-9 Cite
