Reserachers found that high expression of α-enolase was present in metastatic lung cancer cell lines and malignant tumors and was associated with poor overall survival of lung cancer patients.
[Cancer Research]
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Li, H.-J., Ke, F.-Y., Lin, C.-C., Lu, M.-Y., Kuo, Y.-H., Wang, Y.-P., Liang, K.-H., Lin, S.-C., Chang, Y.-H., Chen, H.-Y., Yang, P.-C., & Wu, H.-C. (2021). ENO1 promotes lung cancer metastasis via HGFR and WNT signaling-driven epithelial-mesenchymal transition. Cancer Research. https://doi.org/10.1158/0008-5472.CAN-20-3543 Cite
