Investigators showed that TGF-β induced reprogramming of intracellular amino acid metabolism, which was necessary to promote epithelial–mesenchymal transition in non-small cell lung cancer cells.
[Communications Biology]
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Nakasuka, F., Tabata, S., Sakamoto, T., Hirayama, A., Ebi, H., Yamada, T., Umetsu, K., Ohishi, M., Ueno, A., Goto, H., Sugimoto, M., Nishioka, Y., Yamada, Y., Tomita, M., Sasaki, A. T., Yano, S., & Soga, T. (2021). TGF-β-dependent reprogramming of amino acid metabolism induces epithelial–mesenchymal transition in non-small cell lung cancers. Communications Biology, 4(1), 1–12. https://doi.org/10.1038/s42003-021-02323-7 Cite
