The lncRNA ‘UCA1’ Modulates the Response to Chemotherapy of Ovarian Cancer through Direct Binding to miR-27a-5p and Control of UBE2N Levels

The authors observed that UCA1 a lncRNA previously reported to play an oncogenic role in several malignancies, is overexpressed in the chemoresistant ovarian cancer cell line OAW42-R compared to their chemotherapy sensitive counterpart OAW42.