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QAP14 Suppresses Breast Cancer Stemness and Metastasis via Activation of Dopamine D1 Receptor

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Researchers found that QAP14 inhibited colony formation, cell motility, mammosphere formation and CSC frequency, induced CSC apoptosis and dopamine D1 receptor expression, and increased cAMP/cGMP levels.
[Acta Pharmacologica Sinica]
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Abstract
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