Scientists investigated the mechanisms of selection in childhood B-cell precursor acute lymphoblastic leukemia during induction chemotherapy where maximal cytoreduction occurs.
[Nature Cancer]
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Turati, V. A., Guerra-Assunção, J. A., Potter, N. E., Gupta, R., Ecker, S., Daneviciute, A., Tarabichi, M., Webster, A. P., Ding, C., May, G., James, C., Brown, J., Conde, L., Russell, L. J., Ancliff, P., Inglott, S., Cazzaniga, G., Biondi, A., Hall, G. W., … Enver, T. (2021). Chemotherapy induces canalization of cell state in childhood B-cell precursor acute lymphoblastic leukemia. Nature Cancer, 1–18. https://doi.org/10.1038/s43018-021-00219-3 Cite
