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FTO Downregulation Mediated by Hypoxia Facilitates Colorectal Cancer Metastasis

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Researchers found that fat mass and obesity-associated (FTO) protein levels, but not RNA levels, were downregulated in colorectal cancer (CRC) tissues. Reduced FTO protein expression was correlated with a high recurrence rate and poor prognosis in resectable CRC patients.
[Oncogene]
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