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Deregulation of Protein Phosphatase 2A Inhibitor SET Is Associated with Malignant Progression in Breast Cancer

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SET, an endogenous inhibitor of protein phosphatase 2A, was overexpressed in all subtypes of invasive breast carcinoma tissues. Treatment with SET-targeted siRNAs reduced the motility of MCF-7 and MDA-MB-231 cells in transwell assay.
[Scientific Reports]
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