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Rapamycin Pretreatment Rescues the Bone Marrow AML Cell Elimination Capacity of CAR-T Cells

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Scientists examined the effects of a rapamycin pretreatment of epithelial cell adhesion molecule (EpCAM) chimeric antigen receptor (CAR)-T cells and assessed the in vivo antitumor efficacy of rapamycin pretreated EpCAM CAR-T cells and CD33 CAR-T cells in leukemia xenograft mouse models.
[Clinical Cancer Research]
7992332 {7992332:QC836P8U} apa 50 1 164521 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
Abstract
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