TRPV1 Activation and Internalization Is Part of the LPS-Induced Inflammation in Human iPSC-Derived Cardiomyocytes

Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes from four healthy donors were incubated with lipopolysaccharides, TRPV1 agonist capsaicin or the antagonist capsazepine to investigate the role of transient receptor potential vanilloid 1 (TRPV1) for myocardial inflammation.