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Siglec-6 Is a Novel Target for CAR T-Cell Therapy in Acute Myeloid Leukemia (AML)

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Researchers introduced sialic-acid-binding immunoglobulin-like lectin (Siglec)-6 as a novel target for CAR T-cells in acute myeloid leukemia (AML) and found that Siglec-6 was prevalently expressed on AML cell lines and primary AML blasts, including the subpopulation of AML stem cells.
[Blood]
7992332 {7992332:YCAWDACM} apa 50 1 164887 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
Abstract
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