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An Otopetrin Family Proton Channel Promotes Cellular Acid Efflux Critical for Biomineralization in a Marine Calcifier

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Using the sea urchin larva, the authors examined the otopetrin ortholog otop2l, which is exclusively expressed in the calcifying primary mesenchymal cells that generate the calcitic larval skeleton.
[Proceedings of the National Academy of Sciences of the United States of America]

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