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LRRK2 Is Required for CD38-Mediated NAADP-Ca2+ Signaling and the Downstream Activation of TFEB (Transcription Factor EB) in Immune Cells

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Researchers mechanistically and functionally linked CD38 and LRRK2 as upstream activators of TFEB, a host defense transcription factor and the master transcriptional regulator of the autophagy/lysosome machinery.
[Autophagy]

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Abstract
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