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3-Ketodihydrosphingosine Reductase Maintains ER Homeostasis and Unfolded Protein Response in Leukemia

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Using a sphingolipid network focused CRISPR/Cas9 library screen, scientists identified an endoplasmic reticulum enzyme, 3-Ketodihydrosphingosine reductase, to be essential for leukemia cell maintenance.
[Leukemia]
7992332 {7992332:9XN6BMG6} apa 50 1 165473 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
Abstract
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